Tablet Manufacturer/Distributor: ACI Limited Generic Name: Fexofenadine Hydrochloride 180 mg Tablet
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Indications
Fexofenadine Hydrochloride is used to treat the symptoms of seasonal allergic rhinitis in both adults and children. It's also used to treat the cutaneous signs of chronic idiopathic urticaria that aren't too severe.
Pharmacology
Fexofenadine Hydrochloride is an antihistamine that works by blocking peripheral H1 receptors. After oral administration, it is rapidly absorbed and reaches maximal plasma concentration in 2-3 hours. It doesn't appear to be able to pass through the blood-brain barrier.
Dosage & Administration
Seasonal Allergic Rhinitis-
Adults and children 12 years and older:
Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
In case of impaired renal function: 60 mg once daily
Children from 6 to 11 years:
Tablet: 30 mg twice daily or 60 mg once daily
In case of impaired renal function: 30 mg once daily
Children from 2 to 11 years
Suspension: 30 mg or 5 ml twice daily
In case of impaired renal function: 30 mg or 5 ml once daily
Interaction
When taken with erythromycin or ketoconazole, the plasma levels of Fexofenadine Hydrochloride increased. Fexofenadine Hydrochloride absorption is reduced by antacids that contain aluminum and magnesium hydroxide.
Contraindications
Permethrin is not recommended for people who have a known hypersensitivity to any pyrethroid or permethrin component. Nurses who apply permethrin on a regular basis should wear gloves to protect their hands from discomfort.
Side Effects
Patients who have a known hypersensitivity to Fexofenadine Hydrochloride or any of its constituents should not take it.
Pregnancy & Lactation
US FDA pregnancy category of Fexofenadine Hydrochloride is C. So, Fexofenadine Hydrochloride should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.
Precautions & Warnings
Caution should be exercised in elderly patients and patients with decreased renal function.
Storage Conditions
Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.
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